4-Toluenesulfonyl chloride → 2-n-Butyl-5-tosyloxymethyl-4,5,6,7-tetrahydrobenzo[d]thiazole

HRID 1156968Notes

Reaction equation

HRID 1156968 reaction equation
[C:1]1([CH3:11])[CH:6]=[CH:5][C:4]([S:7](Cl)(=[O:9])=[O:8])=[CH:3][CH:2]=1.[CH2:12]([C:16]1[S:17][C:18]2[CH2:24][CH2:23][CH:22]([CH2:25][OH:26])[CH2:21][C:19]=2[N:20]=1)[CH2:13][CH2:14][CH3:15]>>[CH2:12]([C:16]1[S:17][C:18]2[CH2:24][CH2:23][CH:22]([CH2:25][O:26][S:7]([C:4]3[CH:5]=[CH:6][C:1]([CH3:11])=[CH:2][CH:3]=3)(=[O:9])=[O:8])[CH2:21][C:19]=2[N:20]=1)[CH2:13][CH2:14][CH3:15]

Participants

3

Reactant 2

HCID 73974-Toluenesulfonyl chlorideHCID 129177552-n-Butyl-5-hydroxymethyl-4,5,6,7-tetrahydrobenzo[d]thiazole

Product 1

HCID 543084972-n-Butyl-5-tosyloxymethyl-4,5,6,7-tetrahydrobenzo[d]thiazole

Procedure

The compound is prepared by action of p-toluenesulfonyl chloride on the above derivative (IV), according to the procedure described in Example 1. It is obtained as an undistillable oil which is used crude for the subsequent reactions.

Workup

  1. customIt is obtained as an undistillable oil which

Sources & evidence

ORD record
ord-09fdc0708e1e4e2da9d38c4dba5d59b7
Source dataset
uspto-grants-1982_06
Patent number
US04337343

Reaction notes

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