Hydrochloric Acid → HCID 20534464, compound

HRID 1156990Notes

Reaction equation

HRID 1156990 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:9]23[CH2:17][CH2:16][CH2:15][CH:14]2[CH2:13][N:12]([CH3:18])[CH2:11][CH2:10]3)[CH:6]=[CH:7][CH:8]=1.[ClH:19]>C(OCC)C>[Cl-:19].[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:9]23[CH2:17][CH2:16][CH2:15][CH:14]2[CH2:13][NH+:12]([CH3:18])[CH2:11][CH2:10]3)[CH:6]=[CH:7][CH:8]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 12884445HCID 12884445, compound

Product 1

HCID 20534464HCID 20534464, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

A solution of 4a-(3-methoxyphenyl)-2-methyl-2,3,4,4a,5,6,7,7a-octahydro-1H-2-pyrindine in 100 ml. of diethyl ether was stirred while hydrogen chloride gas was bubbled through the solution. The reaction mixture was stirred for thirty minutes and then filtered. The solid product was recrystallized from diisopropyl ether and isopropanol to provide 4a-(3-methoxyphenyl)-2-methyl-2,3,4,4a,5,6,7,7a-octahydro-1H-2-pyrindinium chloride. M.P. 175°-177° C.

Workup

  1. customwas bubbled through the solution
  2. filtrationfiltered
  3. customThe solid product was recrystallized from diisopropyl ether and isopropanol

Sources & evidence

ORD record
ord-0650273d39ea42b7b1b933a47153de69
Source dataset
uspto-grants-1982_06
Patent number
US04337341

Reaction notes

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