Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 12899265 | HCID 12899265 | — |
| Product | HCID 12899266 | HCID 12899266 | 89.9% |
Reaction Steps
2-Chloroacetylamino-3-fluorothiophenol (2.0 g) was added to 2 N aqueous sodium hydroxide solution (25 ml), followed by stirring at room temperature (25° C.) for 3 hours. The precipitated crystals were filtered, washed with water and dried to obtain 1.5 g of the objective 5-fluoro-2,3-dihydro-1,4-benzothiazine-3-one (m.p. 190°-191° C.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04337357 |
|---|
| Source dataset | uspto-grants-1982_06 |
|---|
| ORD ID | ord-8ebdce678a414d73b98fb22d54e67ec6 |
|---|
| Source note | uspto-grants-1982_06 |
|---|
