5'-Atp → 5'-Adp

HRID 1157078Notes

Reaction equation

HRID 1157078 reaction equation
[CH:1]1[N:5]([C@@H:6]2[O:10][C@@H:9]3[CH2:11][O:12][P:13]([OH:16])([O:15][C@H:8]3[C@H:7]2[OH:17])=[O:14])[C:4]2[NH:18][C:19]([NH2:23])=[N:20][C:21](=[O:22])[C:3]=2[N:2]=1.[P:24]([O:36][CH2:37][C@H:38]1[O:42][C@@H:41]([N:43]2[C:52]3[N:51]=[CH:50][N:49]=[C:47]([NH2:48])[C:46]=3[N:45]=[CH:44]2)[C@H:40]([OH:53])[C@@H:39]1[OH:54])([O:27][P:28]([O:31]P(O)(O)=O)([OH:30])=[O:29])(=[O:26])[OH:25].P(O)(O)(O)=O.N1C(=O)C2NC=NC=2N=C1N>>[P:13]([O:12][CH2:11][C@H:9]1[O:10][C@@H:6]([N:5]2[C:4]3[N:18]=[C:19]([NH2:23])[NH:20][C:21](=[O:22])[C:3]=3[N:2]=[CH:1]2)[C@H:7]([OH:17])[C@@H:8]1[OH:15])([O:26][P:24]([OH:36])([OH:27])=[O:25])(=[O:14])[OH:16].[P:24]([O:36][CH2:37][C@H:38]1[O:42][C@@H:41]([N:43]2[C:52]3[N:51]=[CH:50][N:49]=[C:47]([NH2:48])[C:46]=3[N:45]=[CH:44]2)[C@H:40]([OH:53])[C@@H:39]1[OH:54])([O:27][P:28]([OH:30])([OH:31])=[O:29])(=[O:25])[OH:26]

Participants

5

Reactant 3

HCID 59575'-AtpHCID 1358430512-Amino-1,7-dihydropurin-6-one;phosphoric acidHCID 178418274HCID 178418274, compound

Product 2

HCID 60225'-AdpHCID 135398619Guanosine Diphosphate

Procedure

The cGMP present in the sample is then converted to GMP with phosphodiesterase. The GMP is combined with ATP in the presence of guanine monophosphate kinase to yield guanosine-5′-diphosphate (GDP) and ADP.

Sources & evidence

ORD record
ord-b0b8846a234f4d108aa157a59f0703e9
Source dataset
uspto-grants-2010_10
Patent number
US07807367B2

Reaction notes

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