HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 68521714, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 2-Acetylamino-5-(3-piperidin-1-ylpropoxy)benzoic acid methyl ester | HCID 68523993 | — |
| Product | HCID 68521714 | HCID 68521714 | 100% |
Reaction Steps
2-Acetylamino-5-(3-piperidin-1-ylpropoxy)benzoic acid methyl ester (1.34 g, 4.0 mmol) was treated with 6N HCl (aq.) (20 mL) and heated at reflux temperature for 8 h. The mixture was then cooled and concentrated in vacuo to afford 2-amino-5-(3-piperidin-1-ylpropoxy)benzoic acid dihydrochloride (1.4 g, 4.0 mmol, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07807686B2 |
| Source dataset | uspto-grants-2010_10 |
| ORD ID | ord-aa917166df5442a0a708e41c046e9ad6 |
| Source note | uspto-grants-2010_10 |