HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloride → HCID 57737247, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloride | HCID 312 | — |
| Reactant | Morpholine | HCID 8083 | — |
| Reactant | HCID 59511411 | HCID 59511411 | — |
| Product | HCID 57737247 | HCID 57737247 | 71% |
Reaction Steps
The compound was synthesized from N-(3-{3-[2-({3-[(3-chloropropyl)oxy]-phenyl}amino)-4-pyrimidinyl]pyrazolo[1,5-a]pyridin-2-yl}phenyl)-2,2,2-trifluoroacetamide via chloride displacement with morpholine as described in Example 10, Step D to afford an orange solid in 71% yield. ES-LC/MS m/z 522 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07807673B2 |
| Source dataset | uspto-grants-2010_10 |
| ORD ID | ord-1c5b9a4c3cf34991803aba11a95373ab |
| Source note | uspto-grants-2010_10 |