N-{3-[3-(2-{[3-(1,3-Oxazol-5-yl)phenyl]amino}-4-pyrimidinyl)pyrazolo[1,5-a]pyridin-2-yl]phenyl}-2-(2-thienyl)acetamide → N-{3-[3-(2-{[3-(4-Methyl-1,3-oxazol-5-yl)phenyl]amino}pyrimidin-4-yl)pyrazolo[1,5-a]pyridin-2-yl]phenyl}-2-(2-thienyl)acetamide

Participants

Reaction Steps

The title compound was synthesized from N-{3-[3-(2-chloro-4-pyrimidinyl)pyrazolo[1,5-a]pyridin-2-yl]phenyl}-2-(2-thienyl)acetamide (see Example 2, step B) and 3-(4-methyl-1,3-oxazol-5-yl)aniline following the protocol described in Example 2, step E. The reaction formed a suspension on cooling to rt. The suspension was filtered and provided the title compound in 81% yield.

Provenance & Evidence