HCID 68695108, compound → HCID 68698459, compound

HRID 1157680Notes

Reaction equation

HRID 1157680 reaction equation
[CH3:1][CH:2]([CH2:13][N+:14]([O-])=O)[CH2:3][C:4]([C:7]1[CH:8]=[N:9][CH:10]=[CH:11][CH:12]=1)([OH:6])[CH3:5]>CCO>[NH2:14][CH2:13][CH:2]([CH3:1])[CH2:3][C:4]([C:7]1[CH:8]=[N:9][CH:10]=[CH:11][CH:12]=1)([OH:6])[CH3:5]

Participants

3

Reactant 1

HCID 68695108HCID 68695108, compound

Product 1

HCID 68698459HCID 68698459, compoundYield 84.4%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Stir a mixture of 4-methyl-5-nitro-2-pyridin-3-yl-pentan-2-ol (860 mg, 3.84 mmol) and Pt—C(S) (200 mg) in EtOH (25 mL) at room temperature under hydrogen atmosphere (7 atm) for 24 h. Filter through a pad of Celite® and evaporate to obtain 630 mg (84%) of the title compound.

Workup

  1. filtrationFilter through a pad of Celite®
  2. customevaporate

Sources & evidence

ORD record
ord-5819c264c2664d79a296e1d500c00303
Source dataset
uspto-grants-2010_10
Patent number
US07807691B2

Reaction notes

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