Bromide ion → Raloxifene Bismethyl Ether

HRID 115787Notes

Reaction equation

HRID 115787 reaction equation
[Br-:24].[CH3:1][O:2][C:3](=[O:4])[c:5]1[c:6]2[c:7]([s:8][c:9]1-[c:10]1[cH:11][cH:12][c:13]([O:16][CH3:17])[cH:14][cH:15]1)[cH:18][c:19]([O:22][CH3:23])[cH:20][cH:21]2.[N:25]1([CH2:31][CH2:32][O:33][c:34]2[cH:35][cH:36][c:37]([Mg+:40])[cH:38][cH:39]2)[CH2:26][CH2:27][CH2:28][CH2:29][CH2:30]1.[O:41]1[CH2:42][CH2:43][CH2:44][CH2:45]1>>[C:3](=[O:4])([c:5]1[c:6]2[c:7]([s:8][c:9]1-[c:10]1[cH:11][cH:12][c:13]([O:16][CH3:17])[cH:14][cH:15]1)[cH:18][c:19]([O:22][CH3:23])[cH:20][cH:21]2)[c:37]1[cH:36][cH:35][c:34]([O:33][CH2:32][CH2:31][N:25]2[CH2:26][CH2:27][CH2:28][CH2:29][CH2:30]2)[cH:39][cH:38]1

Participants

5

Reactant 4

HCID 259Bromide ionHCID 8028TetrahydrofuranHCID 543901236-Methoxy-2-(4-Methoxyphenyl)benzo[b]thiophene-3-Carboxylic Acid Methyl EsterHCID 178507025HCID 178507025, compound

Product 1

HCID 10767755Raloxifene Bismethyl Ether

Sources & evidence

ORD record
ord-f42e6a20c5974116971d3cf15f51e5e7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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