HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cesium carbonate → Ethyl 4''-(acetylethylamino)-3''-tert-butyl-4'-[4-(tert-butyldimethylsilanyloxy)butoxy]-[1,1';3',1'']terphenyl-4-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | (4-Bromobutoxy)(tert-butyl)dimethylsilane | HCID 582370 | — |
| Reactant | Ethyl 4''-(acetylethylamino)-3''-tert-butyl-4'-hydroxy[1,1';3',1'']terphenyl-4-carboxylate | HCID 86617903 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | Ethyl 4''-(acetylethylamino)-3''-tert-butyl-4'-[4-(tert-butyldimethylsilanyloxy)butoxy]-[1,1';3',1'']terphenyl-4-carboxylate | HCID 131728358 | 99% |
Reaction Steps
In a manner similar to that of Example 2a, by reacting 260 mg of ethyl 4″-(acetylethylamino)-3″-tert-butyl-4′-hydroxy[1,1′;3′,1″]terphenyl-4-carboxylate (0.56 mmol) in 12 mL of dimethylformamide with 225 mg of caesium carbonate and 0.16 mL of 1-bromo-4-(tert-butyldimethylsilanyloxy)butane, 310 mg of ethyl 4″-(acetylethylamino)-3″-tert-butyl-4′-[4-(tert-butyldimethylsilanyloxy)butoxy]-[1,1′;3′,1″]terphenyl-4-carboxylate (yield=99%) are obtained in the form of an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07807708B2 |
| Source dataset | uspto-grants-2010_10 |
| ORD ID | ord-2590a40f333946a38eaa341bdf71cae5 |
| Source note | uspto-grants-2010_10 |