Potassium Carbonate → HCID 23080252, compound

HRID 1158286Notes

Reaction equation

HRID 1158286 reaction equation
[SH:1][C:2]1[NH:3][CH:4]=[CH:5][N:6]=1.Cl[C:8]1[C:13]([Cl:14])=[CH:12][CH:11]=[CH:10][C:9]=1[N+:15]([O-:17])=[O:16].C(=O)([O-])[O-].[K+].[K+]>C(#N)C>[Cl:14][C:13]1[CH:12]=[CH:11][CH:10]=[C:9]([N+:15]([O-:17])=[O:16])[C:8]=1[S:1][C:2]1[NH:3][CH:4]=[CH:5][N:6]=1

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 185552,3-DichloronitrobenzeneHCID 178527877HCID 178527877, compound

Product 1

HCID 23080252HCID 23080252, compoundYield 94%

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

Acetonitrile (20 ml) suspension of 2-mercaptoimidazole (1.0 g) and 2,3-dichloronitrobenzene (2.1 g), potassium carbonate (1.7 g) was stirred under refluxing for 6.5 hours. The reaction mixture was poured into ice-water. The deposited solids were collected by filtration, and washed with n-hexane. The thus obtained solids were dried, there was obtained 2-(2-chloro-6-nitrophenylthio)imidazole (2.4 g, yield: 94%) as yellow powdery product.

Workup

  1. temperatureunder refluxing for 6.5 hours
  2. filtrationThe deposited solids were collected by filtration
  3. washwashed with n-hexane
  4. customThe thus obtained solids were dried

Sources & evidence

ORD record
ord-a8a2747e17bc4c56a16aa4bbe0670569
Source dataset
uspto-grants-2010_10
Patent number
US07807843B2

Reaction notes

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