HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl(cyclopropylmethyl)amine → Cyclopropyl-(tetrahydro-pyran-4-ylmethyl)-carbamoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl(cyclopropylmethyl)amine | HCID 518069 | — |
| Reactant | Benzyl-cyclopropyl-carbamoyl chloride | HCID 10608488 | — |
| Reactant | N-(oxan-4-ylmethyl)cyclopropanamine | HCID 61269370 | — |
| Solvent | Dichloromethane methanol | HCID 21226129 | — |
| Product | Cyclopropyl-(tetrahydro-pyran-4-ylmethyl)-carbamoyl chloride | HCID 86622396 | — |
Reaction Steps
The title compound is prepared analogously as described for benzyl-cyclopropyl-carbamoyl chloride starting from cyclopropyl-(tetrahydro-pyran-4-ylmethyl)-amine (prepared analogously as described for benzyl-cyclopropylmethyl-amine). TLC, Rf (CH2Cl2/MeOH 95:5)=0.9.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07807709B2 |
| Source dataset | uspto-grants-2010_10 |
| ORD ID | ord-dd207a9a7e5f4cc686ba7ae4b1cf4015 |
| Source note | uspto-grants-2010_10 |