HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-cyclopropyltetrahydro-2H-pyran-4-amine → Cyclopropyl(oxan-4-yl)carbamyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-cyclopropyltetrahydro-2H-pyran-4-amine | HCID 6991952 | — |
| Reactant | HCID 59512477 | HCID 59512477 | — |
| Solvent | Dichloromethane methanol | HCID 21226129 | — |
| Product | Cyclopropyl(oxan-4-yl)carbamyl chloride | HCID 54198639 | — |
Reaction Steps
The title compound is prepared analogously as described for cyclopropyl-(tetrahydro-pyran-2-ylmethyl)-carbamoyl chloride starting from commercially available cyclopropyl-(tetrahydro-pyran-4-yl)-amine. TLC, Rf (CH2Cl2/MeOH 95:5)=0.9.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07807709B2 |
| Source dataset | uspto-grants-2010_10 |
| ORD ID | ord-f7fe6df52bbf4ae48daeb35ab8863681 |
| Source note | uspto-grants-2010_10 |