HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → (R)-3-amino-1-methyl-3,4-dihydrocarbostyril hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | (R)-3-t-butyloxycarbonylamino-1-methyl-3,4-dihydrocarbostyril | HCID 69195875 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | (R)-3-amino-1-methyl-3,4-dihydrocarbostyril hydrochloride | HCID 69196199 | — |
Reaction Steps
(R)-3-t-butyloxycarbonylamino-1-methyl-3,4-dihydrocarbostyril (20 mg) was dissolved in 4 M hydrogen chloride in 1,4-dioxane solution (5 mL) at room temperature. After 1 h the solvent was evaporated under vacuum, and the residue was twice taken up in toluene (5 mL) and evaporated under vacuum to provide (R)-3-amino-1-methyl-3,4-dihydrocarbostyril hydrochloride (25 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07098235B2 |
| Source dataset | uspto-grants-2006_08 |
| ORD ID | ord-7ac6fa017fd64b0fbef0e360df747472 |
| Source note | uspto-grants-2006_08 |