Phenylephrine Hydrochloride → HCID 131728371, compound

HRID 1158778Notes

Reaction equation

[CH2:1]([CH2:8][NH:9][C:10]1[N:15]=[C:14]([C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=2[Cl:22])[C:13]([C:23](O)=[O:24])=[CH:12][N:11]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:26][NH:27][CH2:28][C@H:29]([OH:37])[C:30]1[CH:35]=[CH:34][CH:33]=[C:32]([OH:36])[CH:31]=1.Cl>>[OH:37][CH:29]([C:30]1[CH:35]=[CH:34][CH:33]=[C:32]([OH:36])[CH:31]=1)[CH2:28][N:27]([CH3:26])[C:23]([C:13]1[C:14]([C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=2[Cl:22])=[N:15][C:10]([NH:9][CH2:8][CH2:1][C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=2)=[N:11][CH:12]=1)=[O:24]

Participants

Reactant 2

HCID 5284443Phenylephrine Hydrochloride

HCID 68644555HCID 68644555, compound

Product 1

HCID 131728371HCID 131728371, compound

Procedure

The material is prepared according to the method described in Example 17. starting from 2-(Benzylmethylamino)-4-(2-chlorophenyl)pyrimidine-5-carboxylic acid and L-phenylephrine hydrochloride. M.p.: 139° C.

Workup

customThe material is prepared

Sources & evidence

ORD record: ord-91d78df7f3ee48dc9123a14dc3d980f5
Source dataset: uspto-grants-2010_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07812031B2

Reaction notes

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