Ammonia → 3,4-Dihydro-2H-1-benzopyran-4-amine

HRID 1158802Notes

Reaction equation

HRID 1158802 reaction equation
CO[N:3]=[C:4]1[C:13]2[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=2)[O:7][CH2:6][CH2:5]1.CON=C1C2C(=CC=C(C)C=2)OCC1.N>>[O:7]1[C:8]2[C:13](=[CH:12][CH:11]=[CH:10][CH:9]=2)[CH:4]([NH2:3])[CH2:5][CH2:6]1

Participants

4

Reactant 3

HCID 222AmmoniaHCID 54035320Chroman-4-one O-methyl-oximeHCID 86605441(4E)-N-Methoxy-6-methyl-3,4-dihydro-2H-1-benzopyran-4-imine

Product 1

HCID 49619573,4-Dihydro-2H-1-benzopyran-4-amine

Procedure

The title compound was prepared using the procedure as described in Example 7B, substituting the product of Example 16A for the product of Example 7A. 1H NMR (300 MHz, DMSO-d6) δ ppm 7.32 (dd, J 1.0 and 7.5 Hz, 1H), 7. 05 (m, 1H), 6.81 (m, 1H), 6.70 (dd, J 1.0 and 7.5 Hz, 1H), 4.27-4.08 (m, 2H), 3.83 (t, J 6.0 Hz, 1H), 2.03-1.66 (m, 4H). MS (DCI/NH3) m/e 150 (M+H)+.

Sources & evidence

ORD record
ord-36455fce63114ce58a8e230d7d86b904
Source dataset
uspto-grants-2010_10
Patent number
US07812019B2

Reaction notes

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