HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Cyanophenol → HCID 58636822, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Cyanophenol | HCID 13019 | — |
| Reactant | 3-(5-Hydroxymethyl-2,4-dimethyl-pyridin-3-yloxymethyl)-benzonitrile | HCID 58636803 | — |
| Product | HCID 58636822 | HCID 58636822 | 47.3% |
Reaction Steps
The coupling of 3-(5-hydroxymethyl-2,4-dimethyl-pyridin-3-yloxymethyl)-benzonitrile (26) (1.0 mg, 3.70 mmol) and 4-cyanophenol (885 mg, 7.40 mmol), as described in Example 9, gave 4-[4,6-dimethyl-5-(3-cyano-benzyloxy)-pyridin-3-ylmethoxy]-benzonitrile (69) (646 mg, 47% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07812037B2 |
| Source dataset | uspto-grants-2010_10 |
| ORD ID | ord-2a1c678de0354532b74b62012f3f1673 |
| Source note | uspto-grants-2010_10 |