Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1158998Generated: November 3, 2026

HCID 68644405, compound → HCID 68644634, compound

https://huagongshe.com/reaction/1158998

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 68644405HCID 68644405—
ReactantHCID 178418361HCID 178418361—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 68644634HCID 6864463487%

Reaction Steps

To a solution of 2-(2,4-difluorophenyl)-1-(5-nitro-1H-indazol-1-yl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ol (3.57 g, 8.92 mmol) in methanol (50 ml) was added 5% palladium charcoal (Pd/C) (0.35 g) and hydrogen gas, followed by stirring for 12 hours. The reaction solution was filtered through celite. The filtrate was concentrated through vacuum evaporation to produce the title compound. (Yield 87%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07812045B2
Source datasetuspto-grants-2010_10
ORD IDord-dd968fdd5d114dc3ac5e984d57aa49d0
Source noteuspto-grants-2010_10