Hydrochloric Acid → HCID 131726534, compound

Participants

Reaction Steps

To N-(t-butoxycarbonyl)-(R)-1,3,4,10b-tetrahydro-7-trifluoromethyl-pyrazino[2,1-a]isoindole (37 mg, 0.11 mmol) was added concentrated aqueous hydrogen chloride (1 mL). After 15 min, the solution was concentrated, diluted with water, and lypholized to give (R)-1,3,4,10b-tetrahydro-7-trifluoromethyl-pyrazino[2,1-a]isoindole bis hydrochloric acid salt (33 mg, 99%) as an off white solid.

Provenance & Evidence