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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1159138Generated: October 26, 2026

2,2,2-Trifluoroethyl trifluoromethanesulfonate → 1-(2,2,2-Trifluoro-ethyl)-1H-indole-3-carboxylic acid thiazol-2-ylamide

https://huagongshe.com/reaction/1159138

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,2,2-Trifluoroethyl trifluoromethanesulfonateHCID 80366—
ReactantN-(1,3-thiazol-2-yl)-1H-indole-3-carboxamideHCID 17592646—
Product1-(2,2,2-Trifluoro-ethyl)-1H-indole-3-carboxylic acid thiazol-2-ylamideHCID 59513933—

Reaction Steps

The title compound was prepared using 1H-indole-3-carboxylic acid thiazol-2-ylamide and 2,2,2-trifluoroethyl triflate as R5X.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07812043B2
Source datasetuspto-grants-2010_10
ORD IDord-cb0eba50d9144ebaac0c0aa94cc4b2e5
Source noteuspto-grants-2010_10