HCID 59513982, compound → Indole

HRID 1159158Notes

Reaction equation

HRID 1159158 reaction equation
C(OC(=O)CCSC1SC(NC([C:16]2[C:24]3[C:19](=[CH:20][C:21](C)=[CH:22][CH:23]=3)[N:18](CC3CC3)[CH:17]=2)=O)=NC=1)C.C1(CN2C3C(=CC=C(F)C=3)C(C(NC3SC=C(SCC(O)=O)N=3)=O)=C2)CC1>>[NH:18]1[C:19]2[C:24](=[CH:23][CH:22]=[CH:21][CH:20]=2)[CH:16]=[CH:17]1

Participants

3

Reactant 2

HCID 59513982HCID 59513982, compoundHCID 86610210{2-[(1-Cyclopropylmethyl-6-fluoro-1H-indole-3-carbonyl)-amino]-thiazol-4-ylsulfanyl}-acetic acid

Product 1

HCID 798Indole

Procedure

3-{2-[(1-Cyclopropylmethyl-6-methyl-1H-indole-3-carbonyl)-amino]-thiazol-5-ylsulfanyl}-propionic acid ethyl ester was hydrolysed according to the procedure given in the procedure for the synthesis of {2-[(1-cyclopropylmethyl-6-fluoro-1H-indole-3-carbonyl)-amino]-thiazol-4-ylsulfanyl}-acetic acid

Sources & evidence

ORD record
ord-7c1b353ef74e4aa1a7e2cb4598aae20e
Source dataset
uspto-grants-2010_10
Patent number
US07812043B2

Reaction notes

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