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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1159231Generated: November 1, 2026

2-Methoxyethanol → HCID 24857250, compound

https://huagongshe.com/reaction/1159231

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-MethoxyethanolHCID 8019—
Reactant4-Chlorophenylboronic acidHCID 74299—
Reactant(2S)-2-Amino-3,3-dimethyl-1-butanolHCID 2734079—
ReactantMethyl 5-bromo-6-hydroxynicotinateHCID 2764315—
ProductHCID 24857250HCID 24857250—

Reaction Steps

The title compound was synthesized in analogy to the procedure described for the preparation of Example 6, using 5-bromo-1,6-dihydro-6-oxo-3-pyridinecarboxylic acid methyl ester, 2-methoxy-ethanol (commercially available), 4-chlorophenyl-boronic acid (commercially available) and L-tert-leucinol (commercially available) as starting materials. MS (ISP): 407.4 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07812028B2
Source datasetuspto-grants-2010_10
ORD IDord-b803125c5c8840fa89fbbf544ebe6a88
Source noteuspto-grants-2010_10