HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluorophenylboronic acid → 5-Bromo-3-(4-fluorophenyl)pyrazin-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluorophenylboronic acid | HCID 285645 | — |
| Reactant | 2-Amino-3,5-dibromopyrazine | HCID 620004 | — |
| Product | 5-Bromo-3-(4-fluorophenyl)pyrazin-2-amine | HCID 71463989 | — |
Reaction Steps
The title compound was synthesized in analogy to the procedure described for the preparation of Example 19a using 2-amino-3,5-dibromopyrazine, and 4-fluorophenylboronic acid (commercially available) as starting materials to give the title compound as a white solid, MS (ISP) 268.1, 270.2 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07812028B2 |
| Source dataset | uspto-grants-2010_10 |
| ORD ID | ord-f3da15945c144fc7bd5868687ad80041 |
| Source note | uspto-grants-2010_10 |