反应详情

The product from Example 1A (2.1 g, 11 mmol) in POCl3 (25 mL) was stirred at reflux overnight, allowed to cool to room temperature, poured onto ice, and extracted with ethyl acetate. The organic extract was dried (Na2SO4), filtered, and the filtrate was concentrated under reduced pressure to give 1.2 g of the title compound. 1H NMR (300 MHz, DMSO-D6) δ ppm 8.96 (s, 2H).

1. temperatureat reflux overnight
2. additionpoured onto ice
3. extractionextracted with ethyl acetate
4. extractionThe organic extract
5. dry with materialwas dried (Na2SO4)
6. filtrationfiltered
7. concentrationthe filtrate was concentrated under reduced pressure