Benzene, 1-chloro-3-isocyanato- → N-[4-(3-amino-1-methyl-1H-pyrazolo[3,4-c]pyridin-4-yl)phenyl]-N'-(3-chlorophenyl)urea

참여 물질

역할	이름	HCID	투입량
반응물	Benzene, 1-chloro-3-isocyanato-	HCID 17968	—
반응물	2-Fluoro-5-methylphenyl isocyanate	HCID 2733377	—
반응물	4-(4-Amino-phenyl)-1-methyl-1H-pyrazolo[3,4-c]pyridin-3-ylamine	HCID 68644474	—
생성물	N-[4-(3-amino-1-methyl-1H-pyrazolo[3,4-c]pyridin-4-yl)phenyl]-N'-(3-chlorophenyl)urea	HCID 11710909	—

반응 단계

The title compound was prepared using the procedure described in Example 1E using the product from Example 6A and 1-chloro-3-isocyanato-benzene instead of the product from Example 1D and 1-fluoro-2-isocyanato-4-methyl-benzene. MS (ESI(+)) m/e 393 (M+H)+; 1H NMR (300 MHz, DMSO-D6) δ ppm 3.92 (s, 3H) 4.67 (s, 2H) 7.01-7.06 (m, 1H) 7.29-7.34 (m, 2H) 7.48 (d, J=8.48 Hz, 2H) 7.63 (d, J=8.48 Hz, 2H) 7.73 (s, 1H) 7.95 (s, 1H) 8.87 (s, 1 H) 8.97 (br.s, 2H).

출처 및 근거

DOI	10.6084/m9.figshare.5104873.v1
특허 번호	US07812166B2
출처 데이터셋	uspto-grants-2010_10
ORD ID	ord-1c709f36f0084ea5815e774e32e7d322
출처 메모	uspto-grants-2010_10