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HRID1159521

反应详情

EQUATION

反应方程式

HRID 1159521 的结构方程式

REACTANTS

反应物

2
结构：CC(C)(CO)CBr
HCID142501

3-Bromo-2,2-dimethyl-1-propanol

C5H11BrO

结构：Cl.O=c1[nH]c(C2CCNCC2)cc2ccccc12
HCID23082113

3-(Piperidin-4-yl)isoquinolin-1(2H)-one--hydrogen chloride (1/1)

C14H17ClN2O

PRODUCTS

生成物

1
结构：CC(C)(CO)CN1CCC(c2cc3ccccc3c(=O)[nH]2)CC1
HCID10313560

未命名化合物

收率 15.2%

PROCEDURE

实验过程

By the reaction in the same manner as in Example 2a, using 3-(piperidin-4-yl)-2H-isoquinolin-1-one hydrochloride (510 mg) and 3-bromo-2,2-dimethyl-1-propanol (474 mg), 3-[1-(3-hydroxy-2,2-dimethylpropyl)piperidin-4-yl]-2H-isoquinolin-1-one (92 mg) was obtained.

WORKUP

后处理

  1. customBy the reaction in the same manner as in Example 2a