HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 86618246, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 68718016 | HCID 68718016 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 86618246 | HCID 86618246 | — |
Reaction Steps
1-tert-Butyl 2-methyl 4-{[1-(phenylsulfonyl)-1H-indol-4-yl]methyl}piperazine-1,2-dicarboxylate (0.013 g, 0.025 mmol, Intermediate 50) was dissolved in dichloromethane (1 mL) and TFA (0.5 mL) was added. The mixture was stirred for 1 h and evaporated. Yield: 16 mg (100%). Colorless oil. MS (electronspray; [M+H]+) m/z 414.6.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07812017B2 |
| Source dataset | uspto-grants-2010_10 |
| ORD ID | ord-94e5bbea72d94f4895100cee765d00d3 |
| Source note | uspto-grants-2010_10 |