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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1159800Generated: November 2, 2026

Trifluoroacetic acid → HCID 86618246, compound

https://huagongshe.com/reaction/1159800

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 68718016HCID 68718016—
SolventDichloromethaneHCID 6344—
ProductHCID 86618246HCID 86618246—

Reaction Steps

1-tert-Butyl 2-methyl 4-{[1-(phenylsulfonyl)-1H-indol-4-yl]methyl}piperazine-1,2-dicarboxylate (0.013 g, 0.025 mmol, Intermediate 50) was dissolved in dichloromethane (1 mL) and TFA (0.5 mL) was added. The mixture was stirred for 1 h and evaporated. Yield: 16 mg (100%). Colorless oil. MS (electronspray; [M+H]+) m/z 414.6.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07812017B2
Source datasetuspto-grants-2010_10
ORD IDord-94e5bbea72d94f4895100cee765d00d3
Source noteuspto-grants-2010_10