Sodium Hydroxide → HCID 68880180, compound

Participants

Reaction Steps

{[5-Methoxy-1-(phenylsulfonyl)-1H-indol-4-yl]methyl}dimethylamine trifluoroacetate (127 mg, 0.278 mmol) was refluxed in EtOH (2 ml) and 1 M NaOH (2 ml) for 3 h. The mixture was extracted with DCM The product was purified on Gilson HPLC using 20-40% MeCN in 0.1% TFA. Yield: 54.6 mg (62%); colourless oil.

Provenance & Evidence