HRID1159936

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID21974741

未命名化合物

结构：O=C(Nc1cccc(-c2nn3ccccc3c2-c2ccnc(Cl)n2)c1)c1c(F)cccc1F

HCID59513803

未命名化合物

PRODUCTS

生成物

结构：CN(CCCOc1ccc(N)cc1F)c1nccc(-c2c(-c3cccc(NC(=O)c4c(F)cccc4F)c3)nn3ccccc23)n1

HCID59513855

未命名化合物

PROCEDURE

实验过程

The title compound was prepared from N-{3-[3-(2-chloro-4-pyrimidinyl)pyrazolo-[1,5-a]pyridin-2-yl]phenyl}-2,6-difluorobenzamide and 4-{[3-(diethylamino)-propyl]oxy}-3-fluoroaniline in a manner analogous to Example 27, Step D. HRMS calcd for C37H34F3N7O2: 665.2726; found: 666.2804 (M+H+).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-c588bfbb151f4a51a0fd07748a27ec68
来源数据集: uspto-grants-2010_10
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07812022B2
来源说明: uspto-grants-2010_10

反应 SMILES

Cl[C:2]1[N:7]=[C:6]([C:8]2[C:9]([C:17]3[CH:18]=[C:19]([NH:23][C:24](=[O:33])[C:25]4[C:30]([F:31])=[CH:29][CH:28]=[CH:27][C:26]=4[F:32])[CH:20]=[CH:21][CH:22]=3)=[N:10][N:11]3[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=23)[CH:5]=[CH:4][N:3]=1.[CH2:34]([N:36](CC)[CH2:37][CH2:38][CH2:39][O:40][C:41]1[CH:47]=[CH:46][C:44]([NH2:45])=[CH:43][C:42]=1[F:48])C>>[NH2:45][C:44]1[CH:46]=[CH:47][C:41]([O:40][CH2:39][CH2:38][CH2:37][N:36]([CH3:34])[C:2]2[N:7]=[C:6]([C:8]3[C:9]([C:17]4[CH:18]=[C:19]([NH:23][C:24](=[O:33])[C:25]5[C:26]([F:32])=[CH:27][CH:28]=[CH:29][C:30]=5[F:31])[CH:20]=[CH:21][CH:22]=4)=[N:10][N:11]4[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=34)[CH:5]=[CH:4][N:3]=2)=[C:42]([F:48])[CH:43]=1