反应详情

In a flask were placed ethyl 3-(2-furyl)-3-oxopropanoate (0.5 g), iodomethane (0.14 ml), finely ground potassium carbonate (0.75 g) and acetone (5 ml). The mixture was stirred at reflux for 2 h. A further portion of iodomethane (0.9 mmol, 0.056 ml) and potassium carbonate (0.9 mmol, 0.12 g) were added and the mixture stirred at reflux for 1 h. The reaction mixture was filtered and concentrated under vacuum. Yield (0.5 g, 93%).

1. customIn a flask were placed
2. temperatureat reflux for 2 h
3. stirringthe mixture stirred
4. temperatureat reflux for 1 h
5. filtrationThe reaction mixture was filtered
6. concentrationconcentrated under vacuum
7. customYield (0.5 g, 93%)