反应详情

3-furan-2-yl-2-methyl-3-oxo-propionic acid ethyl ester (49 mg) was added sodium ethoxide (0.22 ml) and 0.5 ml ethanol. A solid precipitates. The solution was stirred at room temperature for 1 h, iodomethane was added and the suspension stirred at room temperature for 3 h. Concentration in vacuo and purification by HPLC gave the expected product.

1. customA solid precipitates
2. additioniodomethane was added
3. stirringthe suspension stirred at room temperature for 3 h
4. concentrationConcentration
5. customin vacuo and purification by HPLC