Pentane → 1352718-94-5

HRID 1160159Notes

Reaction equation

HRID 1160159 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[C:7]([CH2:9]O)[CH:6]=[C:5]([O:11][CH3:12])[N:4]=1.P(Br)(Br)[Br:14].CCCCC>C(Cl)Cl>[Br:14][CH2:9][C:7]1[CH:8]=[C:3]([O:2][CH3:1])[N:4]=[C:5]([O:11][CH3:12])[CH:6]=1

Participants

5

Reactant 3

HCID 8003PentaneHCID 24614Phosphorus tribromideHCID 598131HCID 598131, compound

Product 1

HCID 179649631352718-94-5

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

1 g of (2,6-dimethoxypyridin-4-yl)methanol, prepared according to J. Heterocl. Chem., 1974, 11, 251, is dissolved in 20 ml of CH2Cl2, 0.84 ml of PBr3 is added and then the mixture is left stirring at AT for 10 hours. Pentane is added and the precipitate formed is filtered off, washed with pentane and then dried to produce 850 mg of the expected compound.

Workup

  1. waitthe mixture is left
  2. customthe precipitate formed
  3. filtrationis filtered off
  4. washwashed with pentane
  5. customdried

Sources & evidence

ORD record
ord-72f93910f2e54b2b812774488e5935e9
Source dataset
uspto-grants-2010_10
Patent number
US07816368B2

Reaction notes

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