反应详情

74.2 g of triphenylphosphine (0.28 M) in 200 ml of acetonitrile are added to a solution of 74.5 g of methyl 2-bromomethylbenzoate (0.32 M) in 170 ml of acetonitrile in a 2000 ml reactor. The reaction mixture is refluxed with stirring for one hour and then cooled. 1000 ml of diethyl ether are then added slowly. Stirring is continued for 2 hours. A white precipitate forms. The solid is filtered off and washed with acetone. After drying, 112.6 g of a white powder are obtained (81% yield).

1. temperatureThe reaction mixture is refluxed
2. temperaturecooled
3. stirringStirring
4. waitis continued for 2 hours
5. filtrationThe solid is filtered off
6. washwashed with acetone
7. customAfter drying