HCID 68690984, compound → HCID 68688085, compound

HRID 1160382Notes

Reaction equation

HRID 1160382 reaction equation
[OH:1][CH2:2][CH2:3][C:4]#[C:5][C:6]1[CH:15]=[CH:14][CH:13]=[CH:12][C:7]=1[C:8]([O:10][CH3:11])=[O:9]>[Pd].CO>[OH:1][CH2:2][CH2:3][CH2:4][CH2:5][C:6]1[CH:15]=[CH:14][CH:13]=[CH:12][C:7]=1[C:8]([O:10][CH3:11])=[O:9]

Participants

4

Reactant 1

HCID 68690984HCID 68690984, compound

Product 1

HCID 68688085HCID 68688085, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Conditions

Temperature
70 °C

Procedure

46.6 g (0.023 M) of methyl 2-(4-hydroxybut-1-ynyl)benzoate and 5 g of wet 10% palladium-on-charcoal are added to 900 ml of methanol in a 2000 ml stainless-steel autoclave. The reaction medium is then stirred under hydrogen pressure (10 bar) at 70° C. for 16 hours.

Sources & evidence

ORD record
ord-e42e3f00014a415cb9458d0b8e5407e0
Source dataset
uspto-grants-2010_10
Patent number
US07816397B2

Reaction notes

Loading…