Methyl 4-Formylbenzoate → Methyl 4-(1-hydroxy-3-methylbutyl)benzoate

HRID 1160852Notes

Reaction equation

HRID 1160852 reaction equation
[CH3:1][O:2][C:3](=[O:12])[C:4]1[CH:9]=[CH:8][C:7]([CH:10]=[O:11])=[CH:6][CH:5]=1.[CH2:13]([Mg]Cl)[CH:14]([CH3:16])[CH3:15]>>[CH3:1][O:2][C:3](=[O:12])[C:4]1[CH:9]=[CH:8][C:7]([CH:10]([OH:11])[CH2:13][CH:14]([CH3:16])[CH3:15])=[CH:6][CH:5]=1

Participants

3

Reactant 2

HCID 15294Methyl 4-FormylbenzoateHCID 178418368HCID 178418368, compound

Product 1

HCID 59518172Methyl 4-(1-hydroxy-3-methylbutyl)benzoate

Procedure

This compound is made from 4-formyl-benzoic acid methyl ester and isobutylmagnesium chloride following the general method exemplified in Preparation 1.

Workup

  1. customexemplified in Preparation 1

Sources & evidence

ORD record
ord-62bb8669e3334a2284e40d9c20b21cc5
Source dataset
uspto-grants-2010_10
Patent number
US07816557B2

Reaction notes

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