HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 67153507, compound → HCID 135706016, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 67153507 | HCID 67153507 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 135706016 | HCID 135706016 | 67.5% |
Reaction Steps
To a solution of 2-(4-Benzyloxy-phenyl)-5-trifluoromethyl-pyridine (2.55 g) in ethanol (100 mL) and THF (25 mL) is added Pd/C (5%, 0.253 g), the mixture is stirred under 60 psi of hydrogen overnight. The catalyst is filtered off, concentration of the filtrate gave the title compound (1.25 g, 67.5%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07816557B2 |
| Source dataset | uspto-grants-2010_10 |
| ORD ID | ord-3c15e21724e945d4be4c852838be4053 |
| Source note | uspto-grants-2010_10 |