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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 116101Generated: October 27, 2026

1,1,1-Trifluoro-2-(4-iodo-phenyl)-propan-2-ol → 8-(Isobutylsulfonyl)-2-(4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl)-2,8-diazaspiro[4.5]decan-1-one

https://huagongshe.com/reaction/116101

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,1,1-Trifluoro-2-(4-iodo-phenyl)-propan-2-olHCID 15134939—
Reactant8-(Isobutylsulfonyl)-2,8-diazaspiro[4.5]decan-1-oneHCID 59577951—
Reactant8-(Isobutylsulfonyl)-2-(4-(2,2,2-trifluoro-1-hydroxyethyl)phenyl)-2,8-diazaspiro[4.5]decan-1-oneHCID 59578029—
Product8-(Isobutylsulfonyl)-2-(4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl)-2,8-diazaspiro[4.5]decan-1-oneHCID 59577985—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-18fd4b80f758410da708629a5299ee4f
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)