HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 44198604, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 68645259 | HCID 68645259 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 44198604 | HCID 44198604 | — |
Reaction Steps
To a solution of (4-{2-[2-(4-chloro-phenyl)-5,6-difluoro-benzoimidazol-1-yl]-2-cyclohexyl-acetylamino}-3-fluoro-phenoxy)-acetic acid tert-butyl ester (120 mg, 0.19 mmol) in dichloromethane (5 ml) was added trifluoroacetic acid (1.5 ml). After 2 h, the solvent was removed under reduced pressure. The resulting oil (78 mg, 71%) solidified upon standing in the refrigerator.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07816540B2 |
| Source dataset | uspto-grants-2010_10 |
| ORD ID | ord-ac606d1b26b74f60ad42cace6929c9f0 |
| Source note | uspto-grants-2010_10 |