HRID1161341

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID61716435

未命名化合物

结构：O=C(O)C(C1CCCCC1)n1c(-c2ccc(Cl)cc2)nc2cc(F)c(F)cc21

HCID66619321

未命名化合物

PRODUCTS

生成物

结构：COC(=O)C(C)Oc1ccc(NC(=O)C(C2CCCCC2)n2c(-c3ccc(Cl)cc3)nc3cc(F)c(F)cc32)c(F)c1

HCID68645495

未命名化合物

PROCEDURE

实验过程

This compound was prepared in analogy to example 57, intermediate, from [2-(4-chloro-phenyl)-5,6-difluoro-benzoimidazol-1-yl]-cyclohexyl-acetic acid and 2-(4-amino-3-fluoro-phenoxy)-propionic acid methyl ester.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-4397a0c3eb104d9c8939a6d01560c6b5
来源数据集: uspto-grants-2010_10
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07816540B2
来源说明: uspto-grants-2010_10

反应 SMILES

[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:12]([CH:13]([CH:17]3[CH2:22][CH2:21][CH2:20][CH2:19][CH2:18]3)[C:14]([OH:16])=O)[C:11]3[CH:23]=[C:24]([F:28])[C:25]([F:27])=[CH:26][C:10]=3[N:9]=2)=[CH:4][CH:3]=1.[CH3:29][O:30][C:31](=[O:43])[CH:32]([O:34][C:35]1[CH:40]=[CH:39][C:38]([NH2:41])=[C:37]([F:42])[CH:36]=1)[CH3:33]>>[CH3:29][O:30][C:31](=[O:43])[CH:32]([O:34][C:35]1[CH:40]=[CH:39][C:38]([NH:41][C:14](=[O:16])[CH:13]([N:12]2[C:11]3[CH:23]=[C:24]([F:28])[C:25]([F:27])=[CH:26][C:10]=3[N:9]=[C:8]2[C:5]2[CH:6]=[CH:7][C:2]([Cl:1])=[CH:3][CH:4]=2)[CH:17]2[CH2:22][CH2:21][CH2:20][CH2:19][CH2:18]2)=[C:37]([F:42])[CH:36]=1)[CH3:33]