HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 2-(4-amino-3-fluorophenoxy)propanoate → 2-(4-{2-[2-(4-Chloro-phenyl)-5,6-difluoro-benzoimidazol-1-yl]-2-cyclohexyl-acetylamino}-3-fluoro-phenoxy)-propionic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 2-(4-amino-3-fluorophenoxy)propanoate | HCID 61716435 | — |
| Reactant | [2-(4-Chloro-phenyl)-5,6-difluoro-benzoimidazol-1-yl]-cyclohexyl-acetic acid | HCID 66619321 | — |
| Product | 2-(4-{2-[2-(4-Chloro-phenyl)-5,6-difluoro-benzoimidazol-1-yl]-2-cyclohexyl-acetylamino}-3-fluoro-phenoxy)-propionic acid methyl ester | HCID 68645495 | — |
Reaction Steps
This compound was prepared in analogy to example 57, intermediate, from [2-(4-chloro-phenyl)-5,6-difluoro-benzoimidazol-1-yl]-cyclohexyl-acetic acid and 2-(4-amino-3-fluoro-phenoxy)-propionic acid methyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07816540B2 |
| Source dataset | uspto-grants-2010_10 |
| ORD ID | ord-4397a0c3eb104d9c8939a6d01560c6b5 |
| Source note | uspto-grants-2010_10 |