HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 6-aminonicotinate → 6-{2-[2-(4-Chloro-phenyl)-5,6-difluoro-benzoimidazol-1-yl]-2-cyclohexyl-acetylamino}-nicotinic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 6-aminonicotinate | HCID 737487 | — |
| Reactant | [2-(4-Chloro-phenyl)-5,6-difluoro-benzoimidazol-1-yl]-cyclohexyl-acetic acid | HCID 66619321 | — |
| Reactant | HCID 178523387 | HCID 178523387 | — |
| Product | 6-{2-[2-(4-Chloro-phenyl)-5,6-difluoro-benzoimidazol-1-yl]-2-cyclohexyl-acetylamino}-nicotinic acid methyl ester | HCID 68645264 | — |
Reaction Steps
The title compound was prepared according to Example 22, intermediate c), from [2-(4-chloro-phenyl)-5,6-difluoro-benzoimidazol-1-yl]-cyclohexyl-acetic acid and methyl 6-aminonicotinate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07816540B2 |
| Source dataset | uspto-grants-2010_10 |
| ORD ID | ord-846f773625174814bb2bec55f3902dc0 |
| Source note | uspto-grants-2010_10 |