HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethane, 1-fluoro-2-iodo- → 2-Fluoro-5-methoxy-3-(2-methoxyethoxy)benzaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethane, 1-fluoro-2-iodo- | HCID 69804 | — |
| Reactant | 2-Bromoethyl methyl ether | HCID 80972 | — |
| Reactant | 2-Fluoro-3-hydroxy-5-methoxybenzaldehyde | HCID 59495309 | — |
| Reactant | [2-(2-Fluoro-3-hydroxy-5-methoxyphenyl)-2-[4-(5-methyl-[1,2,4]oxadiazol-3-yl)phenylimino]-1-methylsulfanylethylidene]carbamic acid methyl ester | HCID 72312745 | — |
| Product | 2-Fluoro-5-methoxy-3-(2-methoxyethoxy)benzaldehyde | HCID 59517032 | — |
Reaction Steps
The same procedure was carried out as in Example (3e), except that 2-25 fluoro-3-hydroxy-5-methoxybenzaldehyde [CAS No. 883576-31-6] and 2-bromoethylmethyl ether were used instead of respectively [2-(2-fluoro-3-hydroxy-5-methoxyphenyl)-2-[4-(5-methyl-[1,2,4]oxadiazol-3-yl)phenylimino]-1-methylsulfanylethylidene]carbamic acid methyl ester and 1-fluoro-2-iodoethane, to give the title compound was obtained as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07816522B2 |
| Source dataset | uspto-grants-2010_10 |
| ORD ID | ord-ee2a85b6d5314de9aaf8ae2b6222903d |
| Source note | uspto-grants-2010_10 |