(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal → D-Arabitol
Reaction equation
[CH2:1]([OH:10])[C@@H:2]([C@H:4]([C@@H:6]([CH2:8][OH:9])[OH:7])[OH:5])[OH:3].O=C[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O>>[CH2:8]([OH:9])[C@@H:6]([OH:7])[CH:4]([OH:5])[C@H:2]([OH:3])[CH2:1][OH:10]Participants
Procedure
As can be seen from the results in Table 6, when the production of xylitol was performed through fed-batch culture using the new mutant strain, xylitol was produced for 72 hours was produced in a concentration of 201.3 g/L for 72 hours, suggesting a xylitol yield of 97% and a xylitol productivity of 2.80 g/L/h. Glucose contained in the corncob hydrolyzate was completely consumed during the cell culture process, and 23.7 g/L corresponding to 85% of the total amount (27.9 g/l) of arabinose added remained as arabinose, and 4.2 g/L corresponding to 15% was converted to arabitol. Herein, the concentration of final xylitol concentration (201.3 g/L) to arabitol concentration (4.2 g/L) was 100:2.1, resulting from a decrease arabitol production of 65% compared to the parent strain.
Workup
- customwas completely consumed during the cell culture process, and 23.7 g/L corresponding to 85% of the total amount (27.9 g/l) of arabinose
- additionadded
- concentrationHerein, the concentration of final xylitol concentration (201.3 g/L)
- concentrationto arabitol concentration (4.2 g/L)
Sources & evidence
- ORD record
- ord-f20397c0789342beb2382d86865a2cbe
- Source dataset
- uspto-grants-2010_10
- Patent number
- US07820414B2
Reaction notes
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