Methylamine → HCID 68647627, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of compound 4-chloro-2-ethylsulfanyl-6-phenyl-pyrimidine (1 g, 4 mmol) and aqueous methylamine (0.74 g, 24 mmol) in methanol (20 mL) was stirred at refluxing temperature for 16 hours under nitrogen atmosphere. The reaction mixture was then cooled to temperature in the range of 20-40° C. The solid separated was filtered off and dried under reduced pressure. It was finally titrated with petroleum-ether to afford the title compound as an off white solid.

Provenance & Evidence