4-amino-N-methylbenzene-1-sulfonamide → 4-[4-(4-hydroxy-piperidin-1-yl)-6-phenyl-pyrimidin-2-ylamino]-N-methyl-benzenesulfonamide

Participants

Reaction Steps

A sample of 4-[4-(4-hydroxy-piperidin-1-yl)-6-phenyl-pyrimidin-2-ylamino]-N-methyl-benzenesulfonamide was prepared from compound 1-(2-chloro-6-phenyl-pyrimidin-4-yl)-piperidin-4-ol (0.5 g, 1.74 mmol) and 4-amino-N-methyl-benzenesulfonamide (0.39 g, 1.74 mmol) according to a procedure analogous to that described above in Example 48.

Provenance & Evidence