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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1161669Generated: October 30, 2026

p-Aminoacetophenone → HCID 11517478, compound

https://huagongshe.com/reaction/1161669

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant1-(2-Chloro-6-phenyl-pyrimidin-4-yl)-piperidin-4-olHCID 58626078—
ProductHCID 11517478HCID 11517478—

Reaction Steps

A sample of 1-{4-[4-(4-hydroxy-piperidin-1-yl)-6-phenyl-pyrimidin-2-ylamino]-phenyl}-ethanone hydrochloride was prepared from compound 1-(2-chloro-6-phenyl-pyrimidin-4-yl)-piperidin-4-ol (0.3 g, 1.04 mmol) and 1-(4-amino-phenyl)-ethanone (0.14 g, 1.04 mmol) according to a procedure analogous to that described above in Example 48.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07820654B2
Source datasetuspto-grants-2010_10
ORD IDord-3d74bfc65eaa421e9ee2701339a442b6
Source noteuspto-grants-2010_10