HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenylboronic Acid → 1-(2,6-Diphenyl-pyrimidin-4-yl)-piperidin-4-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenylboronic Acid | HCID 66827 | — |
| Reactant | 1-(2-Chloro-6-phenyl-pyrimidin-4-yl)-piperidin-4-ol | HCID 58626078 | — |
| Product | 1-(2,6-Diphenyl-pyrimidin-4-yl)-piperidin-4-ol | HCID 58626097 | 61% |
Reaction Steps
1-(2,6-Diphenyl-pyrimidin-4-yl)-piperidin-4-ol was prepared from compound 1-(2-chloro-6-phenyl-pyrimidin-4-yl)-piperidin-4-ol and phenyl boronic acid by a procedure analogous to that disclosed in Examples 39 and 95, as described above. Yield: 61%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07820654B2 |
| Source dataset | uspto-grants-2010_10 |
| ORD ID | ord-f7e6d965f6c645a2bdc12830ade7f10f |
| Source note | uspto-grants-2010_10 |