HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chloro-4-methoxyaniline → 4-[4-(3-Chloro-4-methoxy-phenylamino)-6-phenyl-pyrimidin-2-ylamino]-cyclohexanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chloro-4-methoxyaniline | HCID 21441 | — |
| Reactant | HCID 58626065 | HCID 58626065 | — |
| Solvent | 1-Butanol | HCID 263 | — |
| Product | 4-[4-(3-Chloro-4-methoxy-phenylamino)-6-phenyl-pyrimidin-2-ylamino]-cyclohexanol | HCID 11510123 | 53% |
Reaction Steps
4-[4-(3-Chloro-4-methoxy-phenylamino)-6-phenyl-pyrimidin-2-ylamino]-cyclohexanol was prepared by reacting compound 4-(4-chloro-6-phenyl-pyrimidin-2-ylamino)-cyclohexanol (0.15 g, 0.49 mmol) with 3-chloro-4-methoxyaniline (85 mg, 0.54 mmol) in 1-butanol according to the procedure described above. Yield: 53%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07820654B2 |
| Source dataset | uspto-grants-2010_10 |
| ORD ID | ord-8d9f20c7eff848df8ddbfac48ff064d9 |
| Source note | uspto-grants-2010_10 |