Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Acetonitrile | HCID 6342 | — |
| Reactant | 4-Fluorobenzylamine | HCID 67326 | — |
| Reactant | HCID 21098176 | HCID 21098176 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 54704394 | HCID 54704394 | — |
Reaction Steps
4-Fluorobenzylamine (3 eq.) was added to a solution of the crude product of Step 4 in DMF and the reaction mixture was heated to 90° C. for one hour. The title compound was obtained by RP-HPLC (C18, eluting with water and acetonitrile containing 0.1% TFA).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07820660B2 |
|---|
| Source dataset | uspto-grants-2010_10 |
|---|
| ORD ID | ord-40bcfd17ac3846559cd44f8773e1d4b7 |
|---|
| Source note | uspto-grants-2010_10 |
|---|
