HCID 17961693, compound → HCID 17961875, compound

HRID 1161907Notes

Reaction equation

HRID 1161907 reaction equation
[C:1]([O:9][C:10]1[C:15](=[O:16])[N:14]([CH3:17])[C:13]([CH:18]2[CH2:26][C:25]3[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=3)[N:19]2C(OCC2C=CC=CC=2)=O)=[N:12][C:11]=1[C:37]([O:39][CH3:40])=[O:38])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>CCOC(C)=O.[Pd]>[NH:19]1[C:20]2[C:25](=[CH:24][CH:23]=[CH:22][CH:21]=2)[CH2:26][CH:18]1[C:13]1[N:14]([CH3:17])[C:15](=[O:16])[C:10]([O:9][C:1](=[O:8])[C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=2)=[C:11]([C:37]([O:39][CH3:40])=[O:38])[N:12]=1

Participants

4

Reactant 1

HCID 17961693HCID 17961693, compound

Product 1

HCID 17961875HCID 17961875, compound

Reagents, catalysts & solvents 2

HCID 8857Ethyl AcetateSolventHCID 23938PalladiumSolvent

Procedure

Benzyl 2-[5-(benzoyloxy)-4-(methoxycarbonyl)-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl]indoline-1-carboxylate was dissolved in EtOAc and hydrogenated at atmospheric pressure on 10% Pd/C overnight. The crude title product was obtained after filtration and evaporation

Sources & evidence

ORD record
ord-33e08fe7f58b468ba522d3ee1a3c2ed2
Source dataset
uspto-grants-2010_10
Patent number
US07820660B2

Reaction notes

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